Casino Royale is the 21st entry in the official James Bond film series and marked the debut of Daniel Craig as Agent 007. The 2006 film, which rebooted the series, follows Bond (recently promoted to '00' status) as he is assigned a mission to participate in a high stakes poker game involving a banker who launders money for terrorist organizations.

Walking through Venice on a cold February morning, I saw a row of houses along the Grand Canal which I thought I had seen before. It was my first day in Venice, I don’t believe in reincarnation, so my recollection must have come from a film.

And indeed: This is where the ultimate fight in the James Bond film Casino Royale takes place and one of the houses slowly sinks into the water.

1. Question: According to Wikipedia, a 'disused spa', the Kaiserbad, was supposed to be used as the exterior of the Casino Royale. I found a picture: and the 'Grandhotel Pupp serving as the 'Hotel Splendide' where Bond stays during his time in Montenegro.' I only recall seeinng the Pupp, thinking that building was both the casino and the hotel.
2. Follow in the footsteps of the 2006 film for an arresting tour of Venice and the Czech Republic and to lounge in the warmth of the Bahamas and Italy’s Lake Como. And Casino Royale’s stand.
3. In Casino Royale, Bond and Vesper are staying in a suite at a hotel by the famous Piazza San Marco, known as St Mark's square, in Venice.As Vesper is leaving for her secret meeting with Gettler, pretending she's just going to the bank.
4. Casino Royale Filming Locations Only 15 minutes watch time of the movie was contributed to Venice. The film crew managed to travel along with the city of Venice personally. The script of the movie emphasizes the three portions of events.

Casino Royale Venice Hotel Location

You will notice that the red house (second from right in the two first photos), which stands conveniently apart from the houses to the left and right of it, has been replaced by a fake house in the movie. So, you needn’t worry! No real Venetian house was destroyed for this movie.